MPRIME vs ePREP: What Maryland Medicaid Providers Must Do

If you bill Maryland Medicaid — as a residential service agency, an assisted living program that takes the waiver, a home health agency, or any other provider — the portal you use to enroll and revalidate is changing. Maryland Medicaid is retiring ePREP and replacing it with a new system called MPRIME (the Maryland Provider Registration and Information Management Enterprise), going live in October 2026.

Most of this is a routine system swap. But buried in the transition is a timing trap that can get a provider suspended, and it’s worth understanding before it bites you.

Update, September 16, 2026 (PT 28-27): the dates are now firm. ePREP access ends October 1, 2026. It is already read-only. Anything you have not downloaded by 5:00 PM on Wednesday, September 30, 2026 is lost, and the transmittal states that Maryland Medicaid “will not retrieve any documentation for providers who fail to download it before the deadline.” MPRIME launches Tuesday, October 13, 2026. Nothing is required on launch day; the login link comes in a separate transmittal about a week before. Details in the dates section below.

Who this applies to

Every Maryland Medicaid provider. If you have an ePREP account today — RSA, ALF, home health, day services, DDA provider — you’ll be moving to MPRIME.

What’s actually changing

ePREP is Maryland Medicaid’s current online provider enrollment and revalidation portal. MPRIME replaces it. Same core job — how you enroll, revalidate, and manage your Medicaid provider information — new system. Before MPRIME goes live, Maryland Medicaid is putting an application hold in place (a period where new applications and changes pause during the switchover).

The dates that matter — and the trap

• Last day to pull your records from ePREP: Wednesday, September 30, 2026, 5:00 PM. ePREP is read-only now. Download your enrollment application, approval and revalidation letters, uploaded licenses and attachments, and correspondence before then.
• ePREP access ends: October 1, 2026. All providers lose access. Nothing left behind is recoverable.
• MPRIME goes live: Tuesday, October 13, 2026. You are not required to set up or associate your user account on launch day. Any date on or after October 13 works. The MPRIME link arrives by provider transmittal the week before launch.
• The revalidation trap: if your revalidation was scheduled between July 1, 2026 and the October go-live, Maryland Medicaid moved it earlier so it wouldn’t collide with the application hold. They began issuing early revalidation notices on a rolling basis in February, with the final ones out by April.
• You get 90 days from your notice to complete that revalidation before the hold takes effect. Providers who don’t complete it within 90 days may be suspended.

Read that last line twice. If you had a revalidation due this summer or fall, your notice already came early — and if it’s sitting unhandled in an inbox, your 90-day clock may be running out. A suspended Medicaid enrollment means you stop getting paid. This is the part of the memo that actually has teeth.

What to do about it

1. Download your ePREP file this week. Log in, save every document you might ever need to show a surveyor, an auditor, or a managed care organization, and store it where both your administrator and your billing person can find it. Deadline: September 30, 5:00 PM.
2. Check whether you had a revalidation due between July 1 and October 2026. If yes, look for an early revalidation notice (issued February–April) and complete it now — don’t wait for the old due date, it moved up.
3. Catch up on MPRIME training. If you missed the live sessions, the recordings, guidance documents, and FAQ are on the MPRIME Resource and Training Center. Get your billing/enrollment staff through them before October 13.
4. Use the right inbox. All MPRIME questions go to [email protected] — but check the FAQ first; they’ll redirect you to it otherwise. Questions sent to random MDH staff may not be answered.
5. Watch for the launch transmittal. The MPRIME link is coming by transmittal the week of October 6. Don’t let October 13 be a surprise.

Why this is easy to miss

It’s a Medicaid enrollment change, not a licensing or training change — so it lands with your billing person, not your administrator, and the suspension risk is one sentence deep in a transmittal. The providers who get caught aren’t careless; they just filed it under “IT stuff, deal with it later.” Don’t.

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The Care Insider is not affiliated with or endorsed by the Maryland Department of Health or the Office of Health Care Quality. This is operator-to-operator plain-language explanation, not legal or enrollment advice — always confirm your specific revalidation status with Maryland Medicaid and read the original transmittals (PT 59-26, PT 65-26, PT 28-27).